THE ROLE OF ENVIRONMENTAL FACTORS IN THE COURSE OF ACUTE RHEUMATIC FEVER IN CHILDREN
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https://doi.org/10.5281/zenodo.18037453##article.subject##:
acute rheumatic fever, children, ecological factors, social determinants, streptococcal infection, rheumatic heart disease, skin infections, poverty.##article.abstract##
Acute rheumatic fever (ARF) is an autoimmune disease that develops in children following group A betahemolytic
streptococcus (Streptococcus pyogenes) infection and can complicate into rheumatic heart disease (RHD)
with cardiac involvement. This article examines the role of ecological and socio-economic factors in the distribution and
progression of ARF. Studies indicate that household overcrowding, poverty, poor hygiene, limited access to medical care,
and other factors such as skin infections and environmental tobacco smoke significantly increase disease risk. According
to the World Health Organization (WHO), RHD affects an estimated 55 million people and causes approximately
360,000 deaths annually, primarily in developing countries. The article proposes prevention measures based on sources
from WHO, PubMed, and The Lancet. These enriched data are particularly relevant in the context of Central Asia and
Uzbekistan, aiding efforts to reduce the disease burden.
Библиографические ссылки
1. World Health Organization. Rheumatic heart disease fact sheet. 2025.
2. Carapetis JR, et al. Acute rheumatic fever and rheumatic heart disease. Nat Rev Dis Primers. 2016.
3. Baker MG, et al. Risk factors for acute rheumatic fever: A case-control study. Lancet Reg Health West Pac. 2022.
4. Coffey PM, et al. The role of social determinants in group A streptococcal infection, ARF and RHD: Systematic review.
PLoS Negl Trop Dis. 2018.
5. Okello E, et al. Socioeconomic and environmental risk factors among RHD patients in Uganda. PLoS One. 2012.
6. Bennett J, et al. Risk factors for acute rheumatic fever: Literature review and protocol for a case-control study in New
Zealand. Int J Environ Res Public Health. 2019.
7. Zhuang S, et al. The rise and fall of acute rheumatic fever and rheumatic heart disease: A mini review. Front Cardiovasc
Med. 2023.
8. Oliver J, et al. Acute rheumatic fever in children: Recognition and treatment. Paediatr Drugs. 2005.
9. Steer AC. Historical aspects of rheumatic fever. J Paediatr Child Health. 2015.
10. Yokchoo N, et al. The effect of group A streptococcal carrier on the epidemic model of acute rheumatic fever. Theor
Biol Med Model. 2019.
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